Research presented at ENDO 2012: The Endocrine Society 94th Annual Meeting showed that pre diabetic, overweight men with hypogonadism (low testosterone) showed improvements in testosterone levels after lifestyle modifications consisting of calorie and fat reduction and exercise. This was a three armed study of about 900 men with about one third getting lifestyle and exercise modification, another receiving the drug metformin, and a third receiving a placebo. Only in the lifestyle group did testosterone rise. Ideally testosterone is not given in a vacuum, but in conjunction with positive lifestyle program, which alone may raise levels sufficiently. This is the Functional Medicine approach.
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