NSAIDs and Intestinal Injury in Athletes

A study publsiehd in Medicine and Science in Sports and Exericse showed that ingesting ibuprofen before or during exercise has serious consequences for the intestines. During exercise there is less blood supply to the intestines. This makes sense, since you want the blood to be shunted to your muscles, your heart, and you lungs during exercise. Consuming ibuprofen during this period causes more damage to the gut than otherwise. The injury resulted in gut barrier dysfunction. In other words, when damaged, the intestines allow too much into the bloodstream that should really be kept out. This can have cause all sorts of sensitivity reactions from mild to severe. NSAIDs have also been known to cause ulceration, bleeding, perforation, and the formation of diaphragm-like strictures. Athletes are advised not to take ibuprofen before performing exercise. 

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